For months I've been ranting to anyone who'll listen that LC is primarily a disease of nervous system dysfunction, specifically a sympathetic-dominant imbalance. I found a 2020 paper with the same hypothesis?! https://t.co/ppSoVtdMI4
RT @LeitzkeMarco: @jannamoen I recently published a hypothesis paper concerning acute COVID-29 infection targeting alpha7nAChRs https://t.…
RT @renesugar: https://t.co/kxrpCjNTyV "ACh couples to α7 subunitcharacterized nicotinic ACh receptors (α7nAChR’s), in turn stopping the a…
RT @renesugar: https://t.co/kxrpCjNTyV "Muscarinic (M1) agonist network communication to certain neural groups modulates the signal to cre…
The cholinergic anti-inflammatory pathway and its impairment in the case of SARS-2CoV infection. Good visual.⬇️👀
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
RT @renesugar: Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
https://t.co/kxrpCjNTyV "a controlled pro-inflammatory cytokinergic response to the #SARSCoV2 invasion appears unlikely in patients with the aforementioned vagus-compromising, pre-existing conditions."
https://t.co/kxrpCjNTyV "Since controlled cytokine release is imperatively linked to a well-balanced autonomic nervous system (ANS)),"
https://t.co/kxrpCjNTyV "and its involvement as main target of the CAP via catecholaminergic splenic nerve fibers is essential for CAP functionality."
https://t.co/kxrpCjNTyV "The spleen, as the principal source of pro-inflammatory cytokines, amplifies local cytokine liberation up to systemic cytokine storm"
https://t.co/kxrpCjNTyV "Thus, it prevents further transcription and downstream release of NF-κBdependent pro-inflammatory cytokines." "Equilibration between pro- and anti-inflammatory processes is thereby achieved and provides innate immunity without da
https://t.co/kxrpCjNTyV "ACh couples to α7 subunitcharacterized nicotinic ACh receptors (α7nAChR’s), in turn stopping the action of nuclear factor κB (NF-κB), the transcriptional factor (TF)."
https://t.co/kxrpCjNTyV "Muscarinic (M1) agonist network communication to certain neural groups modulates the signal to create a somatotopic efferent vagal impulse (DMV) (Tracey 2002)." "This impulse leads to acetylcholine (ACh) secretion at the site of
https://t.co/kxrpCjNTyV "These central parasympathetic structures are responsible for receiving and processing that vagal afferent signaling (NTS)."
https://t.co/kxrpCjNTyV "DVC stands for a group of vagal neurons (area postrema - AP, ambiguous nucleus - NA, solitary nucleus NTS, dorsal motor nucleus of the vagus - DMV) in the brainstem"
https://t.co/kxrpCjNTyV "CAP controls cytokine release via damage associated afferent vagal signaling onto the dorsal vagal complex (DVC)."
https://t.co/kxrpCjNTyV "The cholinergic anti-inflammatory pathway and hyperinflammation Borovikova and Tracey first described the cholinergic anti-inflammatory pathway (CAP)."
Autonomic balance determines the severity of #COVID19 courses #LongCovid https://t.co/kxrpCjNTyV https://t.co/WYF2QrM1Nl
@erturklab Anything that would help clear #SARSCoV2 S protein? https://t.co/mudvCH8LzX
@jannamoen I recently published a hypothesis paper concerning acute COVID-29 infection targeting alpha7nAChRs https://t.co/RGxblfUYEr
@AngeliaDesselle @MdBreathe Here’s an interesting medical article discussing autonomic nervous system balance determining the outcome of covid infection, and how it can affect cytokine storm, via vagus nerve function. https://t.co/NWRp6cMEYh @P_McCullough
@lazlowoodbine42 @Alex_on_A14 @StephenOxborro1 @carlsmythe @InCytometry @necrobiomicon @Lizzy_Lang7 @EdwardArthur5 @hansel21_ @Crazycdn2 @SwaledaleMutton @dogvoyages @c_drosten You think it's random? One can nurture vagal tone and healthy heart rate variab
@dfreedman7 I advocate for higher vagal tone. Safer and more effective disease prevention. Empowering people. Not pricks. https://t.co/nkDsaC8XVG https://t.co/I88SpAcgZK
@yogarespecter other considerations https://t.co/55JZXQSNYN https://t.co/Paqk5mSbiO The cholinergic anti-inflammatory pathway and hyperinflammation https://t.co/JQOGtHVVgQ
RT @boretrol: Autonomic balance determines the severity of COVID-19 courses https://t.co/B4kF6OKI6K
Autonomic balance determines the severity of COVID-19 courses https://t.co/B4kF6OKI6K
@julierehmeyer @ahandvanish I thought I saw a case study last summer about a post-COVID/Long COVID patient with POTS but everything I’ve found is theoretical. https://t.co/vdEwnh2sbL
RT @BioelectronicM: New hypothesis paper about SARS-CoV2, immune responses, and autonomic nervous system function. https://t.co/FlEA5YwFyG
RT @Parsifaler: The COVID-induced disease I have discovered, Cholinergic Neuron Degeneration Disease, is indeed, the cause of severe COVID.…
The COVID-induced disease I have discovered, Cholinergic Neuron Degeneration Disease, is indeed, the cause of severe COVID. https://t.co/H1xZZHSooI Are Ganglion Cell Layer Thinning along with S Protein Load the factors which determine onset? If so, is i
Autonomic balance determines the severity of COVID-19 courses https://t.co/wdEpSofAET
RT @andrew_flatt: Interesting hypothesis paper suggesting ANS status influences COVID severity. COVID symptoms more severe among those with…
New article: coronavirus; +175 new citations https://t.co/KNv29A04ir #coronavirus #COVID19 #2019ncov https://t.co/u7yZrTJG2x
RT @andrew_flatt: Interesting hypothesis paper suggesting ANS status influences COVID severity. COVID symptoms more severe among those with…
RT @andrew_flatt: Interesting hypothesis paper suggesting ANS status influences COVID severity. COVID symptoms more severe among those with…
RT @andrew_flatt: Interesting hypothesis paper suggesting ANS status influences COVID severity. COVID symptoms more severe among those with…
Interesting hypothesis paper suggesting ANS status influences COVID severity. COVID symptoms more severe among those with lower parasympathetic activity. Reduced HRV is common among high-risk populations. Vagal stimulation may be an effective treatment. h
New hypothesis paper about SARS-CoV2, immune responses, and autonomic nervous system function. https://t.co/FlEA5YwFyG