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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents
|
|---|---|
| Published in |
Lipids in Health and Disease, September 2012
|
| DOI | 10.1186/1476-511x-11-117 |
| Pubmed ID | |
| Authors |
Menuka Pallebage-Gamarallage, Virginie Lam, Ryusuke Takechi, Susan Galloway, Karin Clark, John Mamo |
| Abstract |
Several studies have identified use of non-steroidal-anti-inflammatory drugs and statins for prevention of dementia, but their efficacy in slowing progression is not well understood. Cerebrovascular disturbances are common pathological feature of Alzheimer's disease. We previously reported chronic ingestion of saturated fatty acids (SFA) compromises blood-brain barrier (BBB) integrity resulting in cerebral extravasation of plasma proteins and inflammation. However, the SFA-induced parenchymal accumulation of plasma proteins could be prevented by co-administration of some cholesterol lowering agents. Restoration of BBB dysfunction is clinically relevant, so the purpose of this study was to explore lipid-lowering agents could reverse BBB disturbances induced by chronic ingestion of SFA's. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 1% |
| Netherlands | 1 | 1% |
| Unknown | 75 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 19% |
| Student > Bachelor | 9 | 12% |
| Student > Master | 8 | 10% |
| Researcher | 8 | 10% |
| Student > Doctoral Student | 7 | 9% |
| Other | 10 | 13% |
| Unknown | 20 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 22% |
| Medicine and Dentistry | 13 | 17% |
| Neuroscience | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Psychology | 3 | 4% |
| Other | 12 | 16% |
| Unknown | 25 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2012.
All research outputs
#14,733,275
of 22,678,224 outputs
Outputs from Lipids in Health and Disease
#743
of 1,437 outputs
Outputs of similar age
#103,755
of 170,681 outputs
Outputs of similar age from Lipids in Health and Disease
#20
of 30 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,437 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,681 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.