Title |
Comparative effects of amlodipine and benazepril on Left Atrial Pressure in Dogs with experimentally-induced Mitral Valve Regurgitation
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Published in |
BMC Veterinary Research, September 2012
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DOI | 10.1186/1746-6148-8-166 |
Pubmed ID | |
Authors |
Shuji Suzuki, Ryuji Fukushima, Taisuke Ishikawa, Yuta Yamamoto, Lina Hamabe, Soomin Kim, Rieko Yoshiyuki, Noboru Machida, Ryou Tanaka |
Abstract |
One of the purposes of treatment for dogs with mitral regurgitation (MR) is lowering left atrial pressure (LAP). There has been few study of the amlodipine in dogs with MR and amlodipine's effect on LAP has not been fully evaluated in a quantitative manner because of difficulties in directly measuring LAP. The objective of our study was to compare the short-term effects of amlodipine (0.2 mg/kg PO q12h) vs benazepril (0.5 mg/kg PO q12h), on LAP and echocardiographic parameters in five beagle dogs with experimentally-induced MR. LAP of eight dogs that has own control were measured using radiotelemetry system at baseline and again on days 1, 2, 3, 4, 5, 6, 7 of the drug administration. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Slovenia | 1 | 33% |
Turkey | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
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Iran, Islamic Republic of | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 13% |
Student > Master | 8 | 13% |
Student > Ph. D. Student | 7 | 11% |
Other | 5 | 8% |
Student > Bachelor | 4 | 6% |
Other | 15 | 24% |
Unknown | 15 | 24% |
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Medicine and Dentistry | 20 | 32% |
Veterinary Science and Veterinary Medicine | 18 | 29% |
Agricultural and Biological Sciences | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Business, Management and Accounting | 1 | 2% |
Other | 3 | 5% |
Unknown | 15 | 24% |