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Serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in Vitória, Brazil

Overview of attention for article published in BMC Infectious Diseases, July 2016
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Title
Serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in Vitória, Brazil
Published in
BMC Infectious Diseases, July 2016
DOI 10.1186/s12879-016-1668-y
Pubmed ID
Authors

Creuza Rachel Vicente, Karl-Heinz Herbinger, Günter Fröschl, Camila Malta Romano, Aline de Souza Areias Cabidelle, Crispim Cerutti Junior

Abstract

Dengue is caused by a RNA virus of the family Flaviviridae, which presents four serotypes (DENV-1 to DENV-4) capable of inducing hemorrhage. The purpose of this study was to evaluate the influence of serotype on the outcome of dengue. This cross-sectional study included data from dengue cases with serotyping results that occurred between 2009 and 2013 in Vitória, Espírito Santo, Brazil. Data were accessed through the Information System for Notifiable Diseases. Chi-square test, Fisher exact test, Mann-Whitney U test, and logistic regression were performed to assess associations between different serotypes and dengue severity, while considering gender and age. The sample consisted of 485 laboratory confirmed dengue cases, of which 46.4 % were females, with median age of 26 years. Regarding overall samples, 77.3 % were caused by DENV-1, 16.1 % by DENV-4, 6.4 % by DENV-2, and 0.2 % by DENV-3. Severe dengue affected 6.6 % of all cases, of which 32.3 % of the cases caused by DENV-2, 6.4 % of those caused by DENV-4, 4.5 % of those caused by DENV-1, and none of those caused by DENV-3. Severe dengue was found to be seven times more frequent among cases of DENV-2 than among those of the other serotypes. The present study found that cases of DENV-2 had a higher proportion of severe dengue than among those of DENV-1 and DENV-4. Consequently, early detection of serotypes circulating in the territory could be an important approach to prevent increasing numbers of severe outcomes during dengue outbreaks by predicting the health support needed for early diagnoses and treatment of dengue cases.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 273 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 272 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 40 15%
Student > Bachelor 39 14%
Student > Ph. D. Student 31 11%
Researcher 29 11%
Student > Doctoral Student 10 4%
Other 37 14%
Unknown 87 32%
Readers by discipline Count As %
Medicine and Dentistry 45 16%
Biochemistry, Genetics and Molecular Biology 38 14%
Immunology and Microbiology 25 9%
Agricultural and Biological Sciences 22 8%
Nursing and Health Professions 8 3%
Other 38 14%
Unknown 97 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2017.
All research outputs
#15,380,162
of 22,880,691 outputs
Outputs from BMC Infectious Diseases
#4,483
of 7,690 outputs
Outputs of similar age
#226,023
of 354,871 outputs
Outputs of similar age from BMC Infectious Diseases
#107
of 196 outputs
Altmetric has tracked 22,880,691 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,690 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 196 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.