↓ Skip to main content

Activity of crude extracts from Brazilian cerrado plants against clinically relevant Candida species

Overview of attention for article published in BMC Complementary and Alternative Medicine, July 2016
Altmetric Badge

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
72 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Activity of crude extracts from Brazilian cerrado plants against clinically relevant Candida species
Published in
BMC Complementary and Alternative Medicine, July 2016
DOI 10.1186/s12906-016-1164-3
Pubmed ID
Authors

Amabel Fernandes Correia, Dâmaris Silveira, Yris Maria Fonseca-Bazzo, Pérola Oliveira Magalhães, Christopher William Fagg, Elton Clementino da Silva, Suelí Maria Gomes, Lenora Gandolfi, Riccardo Pratesi, Yanna Karla de Medeiros Nóbrega

Abstract

Medicinal plants have traditionally been used in many parts of the world as alternative medicine. Many extracts and essential oils isolated from plants have disclosed biological activity, justifying the investigation of their potential antimicrobial activity. In this study, the in vitro antifungal activity of six Brazilian Cerrado medicinal plant species were evaluated against clinically relevant Candida species. The crude extract plants were evaluated against American Type Culture Collection (ATCC) standard strains of Candida spp. using disk diffusion method and determining the minimum inhibitory concentration (MIC). The chemical study results were confirmed by HPLC method. All six plant species showed antifungal activity. Among the species studied, Eugenia dysenterica and Pouteria ramiflora showed significant inhibitory activity against C. tropicalis at lowest MIC value of 125 and 500 μg/disc, respectively. The Eugenia dysenterica also disclosed MIC value of 125 μg/disc against C. famata, 250 μg/disc against C. krusei and 500 μg/disc against C. guilliermondii and C. parapsilosis. Pouteria torta, Bauhinia rufa, Erythroxylum daphnites and Erythroxylum subrotundum showed activity against the yeast strains with MIC value of 1000 μg/disc. The chemical study of the most bioactive extracts of Eugenia dysenterica and Pouteria ramiflora revealed catechin derivatives and flavonoids as main components. All six evaluated plant species showed good antifungal potential against several Candida strains. However, E .dysenterica and P. ramiflora showed the higher inhibitory effect against the non-albicans Candida species. Our results may contribute to the continuing search of new natural occurring products with antifungal activity.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 3%
Unknown 70 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 24%
Student > Bachelor 15 21%
Student > Doctoral Student 10 14%
Student > Postgraduate 5 7%
Professor 4 6%
Other 10 14%
Unknown 11 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 19%
Medicine and Dentistry 10 14%
Pharmacology, Toxicology and Pharmaceutical Science 7 10%
Biochemistry, Genetics and Molecular Biology 7 10%
Chemistry 7 10%
Other 13 18%
Unknown 14 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2016.
All research outputs
#6,129,648
of 8,071,125 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,456
of 2,023 outputs
Outputs of similar age
#182,314
of 258,679 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#51
of 88 outputs
Altmetric has tracked 8,071,125 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,023 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,679 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.