Title |
The pathophysiological basis and consequences of fever
|
---|---|
Published in |
Critical Care, July 2016
|
DOI | 10.1186/s13054-016-1375-5 |
Pubmed ID | |
Authors |
Edward James Walter, Sameer Hanna-Jumma, Mike Carraretto, Lui Forni |
Abstract |
There are numerous causes of a raised core temperature. A fever occurring in sepsis may be associated with a survival benefit. However, this is not the case for non-infective triggers. Where heat generation exceeds heat loss and the core temperature rises above that set by the hypothalamus, a combination of cellular, local, organ-specific, and systemic effects occurs and puts the individual at risk of both short-term and long-term dysfunction which, if severe or sustained, may lead to death. This narrative review is part of a series that will outline the pathophysiology of pyrogenic and non-pyrogenic fever, concentrating primarily on the pathophysiology of non-septic causes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 25 | 16% |
United States | 10 | 7% |
Spain | 8 | 5% |
Mexico | 5 | 3% |
Australia | 4 | 3% |
Ecuador | 4 | 3% |
Costa Rica | 4 | 3% |
Malaysia | 3 | 2% |
Colombia | 3 | 2% |
Other | 28 | 18% |
Unknown | 58 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 96 | 63% |
Practitioners (doctors, other healthcare professionals) | 44 | 29% |
Scientists | 8 | 5% |
Science communicators (journalists, bloggers, editors) | 4 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Finland | 1 | <1% |
Czechia | 1 | <1% |
South Africa | 1 | <1% |
Unknown | 987 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 193 | 19% |
Student > Master | 80 | 8% |
Student > Postgraduate | 79 | 8% |
Other | 60 | 6% |
Researcher | 57 | 6% |
Other | 167 | 17% |
Unknown | 354 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 323 | 33% |
Nursing and Health Professions | 82 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 54 | 5% |
Agricultural and Biological Sciences | 28 | 3% |
Biochemistry, Genetics and Molecular Biology | 25 | 3% |
Other | 105 | 11% |
Unknown | 373 | 38% |