@kokyriakidis @aphillippy Some papers on major-allele vs GRC https://t.co/Fpc594cIhl https://t.co/1M7GQMqWTx https://t.co/nsSAysGYZM I think major-allele should improve alignments vs T2T, but am not sure if the advantage is big enough for us to make GRCh39
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RT @naechyun_chen: We address the lack-of-diversity bias using a diversified panel of linear population refs. We use a selective strategy t…
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RT @naechyun_chen: We address the lack-of-diversity bias using a diversified panel of linear population refs. We use a selective strategy t…
574 followers
We address the lack-of-diversity bias using a diversified panel of linear population refs. We use a selective strategy to re-align a small subset of reads to the panel; most reads only need to align once. This method is fast and accurate https://t.co/1M7GQ