Title |
Interleukin 2-regulated in vitro antibody production following a single spinal manipulative treatment in normal subjects
|
---|---|
Published in |
Chiropractic & Manual Therapies, September 2010
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DOI | 10.1186/1746-1340-18-26 |
Pubmed ID | |
Authors |
Julita A Teodorczyk-Injeyan, Marion McGregor, Richard Ruegg, H Stephen Injeyan |
Abstract |
Our recent investigations have demonstrated that cell cultures from subjects, who received a single spinal manipulative treatment in the upper thoracic spine, show increased capacity for the production of the key immunoregulatory cytokine, interleukin-2. However, it has not been determined if such changes influence the response of the immune effector cells. Thus, the purpose of the present study was to determine whether, in the same subjects, spinal manipulation-related augmentation of the in vitro interleukin-2 synthesis is associated with the modulation of interleukin 2-dependent and/or interleukin-2-induced humoral immune response (antibody synthesis). |
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