Title |
Epigenetics and inheritance of phenotype variation in livestock
|
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Published in |
Epigenetics & Chromatin, July 2016
|
DOI | 10.1186/s13072-016-0081-5 |
Pubmed ID | |
Authors |
Kostas A. Triantaphyllopoulos, Ioannis Ikonomopoulos, Andrew J. Bannister |
Abstract |
Epigenetic inheritance plays a crucial role in many biological processes, such as gene expression in early embryo development, imprinting and the silencing of transposons. It has recently been established that epigenetic effects can be inherited from one generation to the next. Here, we review examples of epigenetic mechanisms governing animal phenotype and behaviour, and we discuss the importance of these findings in respect to animal studies, and livestock in general. Epigenetic parameters orchestrating transgenerational effects, as well as heritable disorders, and the often-overlooked areas of livestock immunity and stress, are also discussed. We highlight the importance of nutrition and how it is linked to epigenetic alteration. Finally, we describe how our understanding of epigenetics is underpinning the latest cancer research and how this can be translated into directed efforts to improve animal health and welfare. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 18% |
United States | 2 | 12% |
France | 1 | 6% |
Germany | 1 | 6% |
Australia | 1 | 6% |
Unknown | 9 | 53% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 65% |
Scientists | 6 | 35% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | <1% |
Switzerland | 1 | <1% |
Mexico | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 242 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 41 | 17% |
Student > Bachelor | 36 | 15% |
Researcher | 30 | 12% |
Student > Postgraduate | 30 | 12% |
Student > Master | 28 | 11% |
Other | 35 | 14% |
Unknown | 47 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 98 | 40% |
Biochemistry, Genetics and Molecular Biology | 65 | 26% |
Veterinary Science and Veterinary Medicine | 13 | 5% |
Medicine and Dentistry | 5 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 2% |
Other | 6 | 2% |
Unknown | 56 | 23% |