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Antifungal activity of redox-active benzaldehydes that target cellular antioxidation

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, May 2011
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Title
Antifungal activity of redox-active benzaldehydes that target cellular antioxidation
Published in
Annals of Clinical Microbiology and Antimicrobials, May 2011
DOI 10.1186/1476-0711-10-23
Pubmed ID
Authors

Jong H Kim, Kathleen L Chan, Noreen Mahoney, Bruce C Campbell

Abstract

Disruption of cellular antioxidation systems should be an effective method for control of fungal pathogens. Such disruption can be achieved with redox-active compounds. Natural phenolic compounds can serve as potent redox cyclers that inhibit microbial growth through destabilization of cellular redox homeostasis and/or antioxidation systems. The aim of this study was to identify benzaldehydes that disrupt the fungal antioxidation system. These compounds could then function as chemosensitizing agents in concert with conventional drugs or fungicides to improve antifungal efficacy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
United States 1 2%
Belgium 1 2%
Unknown 61 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 14%
Researcher 9 14%
Student > Master 8 13%
Student > Doctoral Student 7 11%
Student > Bachelor 7 11%
Other 12 19%
Unknown 12 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 39%
Chemistry 8 13%
Biochemistry, Genetics and Molecular Biology 5 8%
Medicine and Dentistry 4 6%
Engineering 2 3%
Other 3 5%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2012.
All research outputs
#21,095,110
of 23,742,253 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#546
of 625 outputs
Outputs of similar age
#105,253
of 113,144 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#4
of 4 outputs
Altmetric has tracked 23,742,253 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 625 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,144 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.