Title |
Adenosine-5'-triphosphate (ATP) supplementation improves low peak muscle torque and torque fatigue during repeated high intensity exercise sets
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Published in |
Journal of the International Society of Sports Nutrition, April 2022
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DOI | 10.1186/1550-2783-9-48 |
Pubmed ID | |
Authors |
John A Rathmacher, John C Fuller, Shawn M Baier, Naji N Abumrad, Hector F Angus, Rick L Sharp |
Abstract |
Intracellular concentrations of adenosine-5'-triphosphate (ATP) are many times greater than extracellular concentrations (1-10 mM versus 10-100 nM, respectively) and cellular release of ATP is tightly controlled. Transient rises in extracellular ATP and its metabolite adenosine have important signaling roles; and acting through purinergic receptors, can increase blood flow and oxygenation of tissues; and act as neurotransmitters. Increased blood flow not only increases substrate availability but may also aid in recovery through removal of metabolic waste products allowing muscles to accomplish more work with less fatigue. The objective of the present study was to determine if supplemental ATP would improve muscle torque, power, work, or fatigue during repeated bouts of high intensity resistance exercise. |
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