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Hospitalization for musculoskeletal disorders in rheumatoid arthritis patients: a population-based study

Overview of attention for article published in BMC Musculoskeletal Disorders, July 2016
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2 tweeters

Citations

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4 Dimensions

Readers on

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18 Mendeley
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Title
Hospitalization for musculoskeletal disorders in rheumatoid arthritis patients: a population-based study
Published in
BMC Musculoskeletal Disorders, July 2016
DOI 10.1186/s12891-016-1142-4
Pubmed ID
Authors

Marina Amaral de Ávila Machado, Sasha Bernatsky, Louis Bessette, Hacene Nedjar, Elham Rahme

Abstract

Rheumatoid arthritis (RA) patients failing disease modifying antirheumatic drugs (DMARDs) may undergo anti-Tumor Necrosis Factor (anti-TNF) therapy. Using the Quebec health services administrative databases, we examined the rates of musculoskeletal (MSD)-related hospitalizations among RA patients receiving anti-TNF, DMARDs, and neither of those therapies (non-users). Matched cohort analyses were performed separately in 2002-2006 and 2007-2011. In each cohort, DMARD and non-user groups were formed to 3-1 match the anti-TNF users on age, sex, date of RA diagnosis, high-dimensional propensity score and date of the first anti-TNF dispensation (index-date). Non-users did not use DMARDs or anti-TNF drugs during the year before the index-date and in the 90 days post, but used at least one of these medications in the study period. During 2002-2006, 557 anti-TNF users were matched to 1144 DMARD users and to 656 non-users, compared to 690, 1651, and 532 patients, respectively during 2007-2011. The crude rates of MSD-related hospitalizations in the anti-TNF, DMARD and non-users groups were respectively: 8.2/100, 6.4/100 and 10.5/100 patient-years in 2002-2006, and 6.9/100, 4.8/100, and 8.6/100 patient-years in 2007-2011. In multivariable Cox regression models, the hazard ratios of MSD-related hospitalizations (95 % confidence interval) were: 0.95 (0.60; 1.50) for anti-TNF and 0.69 (0.46; 1.02) for DMARD users, versus non-users in 2002-06, and 0.65 (0.37; 1.14) and 0.40 (0.24; 0.66), respectively in 2007-2011. The MSD-related hospitalization risk was lower in RA patients using DMARD therapy and similar in those using anti-TNF therapy with or without DMARDs as compared to those not using either of these therapies during the study period.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 22%
Professor 2 11%
Student > Bachelor 2 11%
Researcher 2 11%
Student > Master 2 11%
Other 2 11%
Unknown 4 22%
Readers by discipline Count As %
Medicine and Dentistry 9 50%
Pharmacology, Toxicology and Pharmaceutical Science 2 11%
Nursing and Health Professions 2 11%
Biochemistry, Genetics and Molecular Biology 1 6%
Unknown 4 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2017.
All research outputs
#6,356,325
of 11,191,240 outputs
Outputs from BMC Musculoskeletal Disorders
#1,211
of 2,316 outputs
Outputs of similar age
#122,798
of 264,794 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#38
of 78 outputs
Altmetric has tracked 11,191,240 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,316 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,794 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.