Plasma levels of a methadone constant rate infusion and their corresponding effects on thermal and mechanical nociceptive thresholds in dogs

plasma levels of a methadone CRI & their corresponding effects on thermal &mechanical nociceptive thresholds in dogs. A methadone CRI of 0.1 mg kg− 1 h− 1 for 3 days after a loading dose results in steady #antinociceptive effects in healthy dogs ht