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Longitudinal associations between bone and adipose tissue biochemical markers with bone mineralization in boys during puberty

Overview of attention for article published in BMC Pediatrics, July 2016
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Title
Longitudinal associations between bone and adipose tissue biochemical markers with bone mineralization in boys during puberty
Published in
BMC Pediatrics, July 2016
DOI 10.1186/s12887-016-0647-1
Pubmed ID
Authors

Donvina Vaitkeviciute, Evelin Lätt, Jarek Mäestu, Toivo Jürimäe, Meeli Saar, Priit Purge, Katre Maasalu, Jaak Jürimäe

Abstract

We investigated longitudinal relationships between the biochemical markers of bone and adipose tissue with bone mineral content (BMC), bone mineral density (BMD), moderate-to-vigorous physical activity (MVPA) and sedentary time (SED) in pubertal boys. Ninety-six boys (11.9 ± 0.6 years old) were measured at baseline, after 12 and 24 months. Body composition (fat mass [FM], lean body mass [LBM]), and whole body (WB), lumbar spine (LS) and femoral neck (FN) BMD and BMC were assessed. Additionally, serum leptin, adiponectin, osteocalcin (OC) and C-terminal telopeptide of type I collagen (CTX) were measured. OC had a strong longitudinal inverse effect on changes in WB_BMD (p < 0.001) and LS_BMD (p = 0.021), while CTX had an inverse effect only on changes in FN_BMD (p = 0.011). Leptin had an inverse effect on changes in WB_BMC/WB_BMD (p = 0.001), FN_BMD (p = 0.002) and LS_BMD (p = 0.001). MVPA showed a longitudinal inverse effect on changes in leptin (p = 0.030), however no longitudinal effect of SED to biochemical markers of bone and adipose tissue was found. Bone metabolism markers have negative effect on bone mineral accrual during puberty. Increases in MVPA affect leptin, suggesting a positive link of MVPA through leptin metabolism on increases in bone mineralization during puberty.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 14%
Student > Ph. D. Student 7 11%
Student > Master 7 11%
Researcher 6 9%
Other 3 5%
Other 10 16%
Unknown 22 34%
Readers by discipline Count As %
Sports and Recreations 10 16%
Medicine and Dentistry 7 11%
Nursing and Health Professions 5 8%
Biochemistry, Genetics and Molecular Biology 3 5%
Social Sciences 3 5%
Other 7 11%
Unknown 29 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2016.
All research outputs
#17,811,358
of 22,881,154 outputs
Outputs from BMC Pediatrics
#2,264
of 3,014 outputs
Outputs of similar age
#265,134
of 363,720 outputs
Outputs of similar age from BMC Pediatrics
#34
of 51 outputs
Altmetric has tracked 22,881,154 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,014 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 363,720 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.