↓ Skip to main content

Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene

Overview of attention for article published in Respiratory Research, October 2012
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
58 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene
Published in
Respiratory Research, October 2012
DOI 10.1186/1465-9921-13-92
Pubmed ID
Authors

Jimmy Fourtounis, I-Ming Wang, Marie-Claude Mathieu, David Claveau, Tenneille Loo, Aimee L Jackson, Mette A Peters, Alex G Therien, Yves Boie, Michael A Crackower

Abstract

Oxidative Stress contributes to the pathogenesis of many diseases. The NRF2/KEAP1 axis is a key transcriptional regulator of the anti-oxidant response in cells. Nrf2 knockout mice have implicated this pathway in regulating inflammatory airway diseases such as asthma and COPD. To better understand the role the NRF2 pathway has on respiratory disease we have taken a novel approach to define NRF2 dependent gene expression in a relevant lung system.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 28%
Student > Bachelor 12 21%
Student > Ph. D. Student 12 21%
Professor > Associate Professor 3 5%
Other 3 5%
Other 5 9%
Unknown 7 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 40%
Medicine and Dentistry 11 19%
Biochemistry, Genetics and Molecular Biology 10 17%
Immunology and Microbiology 2 3%
Neuroscience 2 3%
Other 3 5%
Unknown 7 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2012.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Respiratory Research
#2,702
of 3,062 outputs
Outputs of similar age
#149,644
of 192,302 outputs
Outputs of similar age from Respiratory Research
#21
of 23 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,302 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.