Telomere length (TL) vs Mortality in COPD (10-y follow-up) — Lowest tertile of TL had risk of death HR=5.48 (1.23–24.42) p=.026 — Accelerated telomere shortening=progressive worsening of pulmonary gas exchange, lung hyperinflation, extrapulmonary affection
RT @pulmonary_rehab: There is an association between accelerated telomere shortening and progressive lang function worsening and extrapulmo…
There is an association between accelerated telomere shortening and progressive lang function worsening and extrapulmonary affection in COPD patients. Persistently shorter telomeres over this observation time increase the risk for all-cause mortality. http