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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq
|
|---|---|
| Published in |
Genome Medicine, July 2016
|
| DOI | 10.1186/s13073-016-0335-7 |
| Pubmed ID | |
| Authors |
David Redmond, Asaf Poran, Olivier Elemento |
| Abstract |
Accurate characterization of the repertoire of the T-cell receptor (TCR) alpha and beta chains is critical to understanding adaptive immunity. Such characterization has many applications across such fields as vaccine development and response, clone-tracking in cancer, and immunotherapy. Here we present a new methodology called single-cell TCRseq (scTCRseq) for the identification and assembly of full-length rearranged V(D)J T-cell receptor sequences from paired-end single-cell RNA sequencing reads. The method allows accurate identification of the V(D)J rearrangements for each individual T-cell and has the novel ability to recover paired alpha and beta segments. Source code is available at https://github.com/ElementoLab/scTCRseq . |
X Demographics
The data shown below were collected from the profiles of 27 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 48% |
| Austria | 1 | 4% |
| United Kingdom | 1 | 4% |
| Belgium | 1 | 4% |
| France | 1 | 4% |
| Unknown | 10 | 37% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 14 | 52% |
| Members of the public | 13 | 48% |
Mendeley readers
The data shown below were compiled from readership statistics for 269 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Germany | 1 | <1% |
| South Africa | 1 | <1% |
| Unknown | 266 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 65 | 24% |
| Researcher | 60 | 22% |
| Student > Master | 25 | 9% |
| Student > Bachelor | 20 | 7% |
| Other | 14 | 5% |
| Other | 33 | 12% |
| Unknown | 52 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 73 | 27% |
| Agricultural and Biological Sciences | 54 | 20% |
| Immunology and Microbiology | 38 | 14% |
| Medicine and Dentistry | 19 | 7% |
| Engineering | 8 | 3% |
| Other | 20 | 7% |
| Unknown | 57 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2022.
All research outputs
#1,846,082
of 24,520,187 outputs
Outputs from Genome Medicine
#411
of 1,512 outputs
Outputs of similar age
#34,558
of 373,480 outputs
Outputs of similar age from Genome Medicine
#11
of 23 outputs
Altmetric has tracked 24,520,187 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,512 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.1. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 373,480 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.