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Can EGFR-TKIs be used in first line treatment for advanced non-small cell lung cancer based on selection according to clinical factors ? -- A literature-based meta-analysis

Overview of attention for article published in Journal of Hematology & Oncology, October 2012
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Title
Can EGFR-TKIs be used in first line treatment for advanced non-small cell lung cancer based on selection according to clinical factors ? -- A literature-based meta-analysis
Published in
Journal of Hematology & Oncology, October 2012
DOI 10.1186/1756-8722-5-62
Pubmed ID
Authors

Chongrui Xu, Qing Zhou, Yi-long Wu

Abstract

In the first line treatment of non-small cell lung cancer (NSCLC), several clinical trials have shown that not all NSCLC patients can benefit from treatment with tyrosine kinase inhibitors (TKIs) than receiving chemotherapy. Some trials treated patients with TKI according to their clinical characteristics. A few studies only chose patients with an epidermal growth factor receptor (EGFR) mutation for TKI therapy. We aimed to determine whether patients could be treated with TKIs based on clinical factors in the first-line setting.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
United States 1 3%
Unknown 33 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Bachelor 5 14%
Student > Ph. D. Student 4 11%
Other 3 9%
Student > Master 3 9%
Other 8 23%
Unknown 6 17%
Readers by discipline Count As %
Medicine and Dentistry 13 37%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Biochemistry, Genetics and Molecular Biology 3 9%
Unspecified 2 6%
Nursing and Health Professions 2 6%
Other 4 11%
Unknown 8 23%