↓ Skip to main content

Retinal regeneration by transplantation of retinal tissue derived from human embryonic or induced pluripotent stem cells

Overview of attention for article published in Inflammation and Regeneration, April 2016
Altmetric Badge

Mentioned by

facebook
1 Facebook page

Readers on

mendeley
25 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Retinal regeneration by transplantation of retinal tissue derived from human embryonic or induced pluripotent stem cells
Published in
Inflammation and Regeneration, April 2016
DOI 10.1186/s41232-016-0004-7
Pubmed ID
Authors

Hiroshi Shirai, Michiko Mandai

Abstract

Rodent studies have recently demonstrated substantial integration of transplanted photoreceptors, with potential synaptic connection and functional restoration. Consequently, photoreceptor transplantation therapy for retinitis pigmentosa is attracting a growing interest in the field of translational research. Differentiation strategies for the formation of three-dimensional (3D) retinal tissue that are suitable for graft preparation have also been introduced via the use of human embryonic stem cells (hESCs) and human induced pluripotent stem cells. We have recently shown that hESC-derived retinal tissue (hESC-retina) can survive, mature, and potentially integrate with host secondary neurons following transplantation into two established primate models of retinal degeneration. Our data demonstrated the feasibility of deploying hESC-retina transplantation as a new remedy with which to restore the vision of patients with end-stage retinal degenerative diseases. In the present mini-review, we provide a short introduction of photoreceptor transplantation research.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 20%
Student > Ph. D. Student 4 16%
Researcher 4 16%
Student > Master 3 12%
Student > Postgraduate 2 8%
Other 4 16%
Unknown 3 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 24%
Medicine and Dentistry 4 16%
Biochemistry, Genetics and Molecular Biology 3 12%
Neuroscience 3 12%
Immunology and Microbiology 1 4%
Other 3 12%
Unknown 5 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2016.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Inflammation and Regeneration
#242
of 258 outputs
Outputs of similar age
#269,622
of 312,469 outputs
Outputs of similar age from Inflammation and Regeneration
#4
of 4 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 258 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,469 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.