Title |
Versican expression in canine carcinomas in benign mixed tumours: is there an association with clinical pathological factors, invasion and overall survival?
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Published in |
BMC Veterinary Research, October 2012
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DOI | 10.1186/1746-6148-8-195 |
Pubmed ID | |
Authors |
Karine A Damasceno, Angélica C Bertagnolli, Alessandra Estrela-Lima, Lorena GR Ribeiro, Bruna S Rabelo, Cecília B Campos, André LB Barros, Geovanni D Cassali |
Abstract |
Components of the extracellular matrix have been studied in an attempt to elucidate the mechanisms involved in the biological behaviour of tumours. The presence of the proteoglycan versican has been strongly associated with cancer development and progression. However, relationship between versican expression and clinical pathological factors and overall survival has not been previously studied in veterinary medicine. Carcinomas in benign mixed tumours (CBMTs) are one of the most common malignant tumours in female canines and can serve as models for studies of tumour progression. The aim of this study was to evaluate the expression of versican in in situ and invasive carcinomatous areas of canine CBMTs and to evaluate possible associations of versican expression with other classic prognostic factors and overall survival. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Australia | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 3% |
Brazil | 1 | 3% |
Unknown | 37 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 9 | 23% |
Other | 6 | 15% |
Student > Postgraduate | 6 | 15% |
Student > Doctoral Student | 2 | 5% |
Researcher | 2 | 5% |
Other | 5 | 13% |
Unknown | 9 | 23% |
Readers by discipline | Count | As % |
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Veterinary Science and Veterinary Medicine | 15 | 38% |
Medicine and Dentistry | 6 | 15% |
Agricultural and Biological Sciences | 5 | 13% |
Chemical Engineering | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 3 | 8% |
Unknown | 8 | 21% |