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Dynamic simulations on the mitochondrial fatty acid Beta-oxidation network

Overview of attention for article published in BMC Systems Biology, January 2009
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1 Facebook page
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1 YouTube creator

Citations

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29 Dimensions

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79 Mendeley
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1 CiteULike
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Title
Dynamic simulations on the mitochondrial fatty acid Beta-oxidation network
Published in
BMC Systems Biology, January 2009
DOI 10.1186/1752-0509-3-2
Pubmed ID
Authors

Robert Modre-Osprian, Ingrid Osprian, Bernhard Tilg, Günter Schreier, Klaus M Weinberger, Armin Graber

Abstract

The oxidation of fatty acids in mitochondria plays an important role in energy metabolism and genetic disorders of this pathway may cause metabolic diseases. Enzyme deficiencies can block the metabolism at defined reactions in the mitochondrion and lead to accumulation of specific substrates causing severe clinical manifestations. Ten of the disorders directly affecting mitochondrial fatty acid oxidation have been well-defined, implicating episodic hypoketotic hypoglycemia provoked by catabolic stress, multiple organ failure, muscle weakness, or hypertrophic cardiomyopathy. Additionally, syndromes of severe maternal illness (HELLP syndrome and AFLP) have been associated with pregnancies carrying a fetus affected by fatty acid oxidation deficiencies. However, little is known about fatty acids kinetics, especially during fasting or exercise when the demand for fatty acid oxidation is increased (catabolic stress).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 4%
Germany 2 3%
Poland 1 1%
Chile 1 1%
Unknown 72 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 29%
Student > Ph. D. Student 20 25%
Student > Master 9 11%
Student > Bachelor 6 8%
Other 5 6%
Other 9 11%
Unknown 7 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 33%
Medicine and Dentistry 14 18%
Biochemistry, Genetics and Molecular Biology 13 16%
Nursing and Health Professions 3 4%
Engineering 3 4%
Other 12 15%
Unknown 8 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2017.
All research outputs
#18,319,742
of 22,684,168 outputs
Outputs from BMC Systems Biology
#834
of 1,142 outputs
Outputs of similar age
#157,807
of 169,282 outputs
Outputs of similar age from BMC Systems Biology
#12
of 13 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,142 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,282 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.