Title |
Delivery type not associated with global methylation at birth
|
---|---|
Published in |
Clinical Epigenetics, June 2012
|
DOI | 10.1186/1868-7083-4-8 |
Pubmed ID | |
Authors |
Shama Virani, Dana C Dolinoy, Sindhu Halubai, Tamara R Jones, Steve E Domino, Laura S Rozek, Muna S Nahar, Vasantha Padmanabhan |
Abstract |
Birth by cesarean delivery (CD) as opposed to vaginal delivery (VD) is associated with altered health outcomes later in life, including respiratory disorders, allergies and risk of developing type I diabetes. Epigenetic gene regulation is a proposed mechanism by which early life exposures affect later health outcomes. Previously, type of delivery has been found to be associated with differences in global methylation levels, but the sample sizes have been small. We measured global methylation in a large birth cohort to identify whether type of delivery is associated with epigenetic changes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 33% |
Canada | 1 | 33% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 22% |
Student > Master | 8 | 18% |
Student > Ph. D. Student | 6 | 13% |
Professor > Associate Professor | 4 | 9% |
Student > Doctoral Student | 3 | 7% |
Other | 7 | 16% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 33% |
Agricultural and Biological Sciences | 8 | 18% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Nursing and Health Professions | 3 | 7% |
Neuroscience | 2 | 4% |
Other | 5 | 11% |
Unknown | 8 | 18% |