Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction

"Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction" Hung C, Li G, Wu J, Liang J, Wang X. Genome Biol 2021-03-10. https://t.co/GwSkXUr8Nw https://t.co/kUfWvAFLQk

RT @GenomeBiology: Huang, Li, Wu, Liang and Wang present a base-editing screen that takes into account editing efficiency to look at the ef…

Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction https://t.co/pW4FFAibOX

Huang, Li, Wu, Liang and Wang present a base-editing screen that takes into account editing efficiency to look at the effects of 9000 variants in BRCA1 and BRCA2. Of 910 loss-of-function variants, 185 have been annotated as clinically benign https://t.co/d