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Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins

Overview of attention for article published in BMC Molecular and Cell Biology, October 2012
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Title
Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins
Published in
BMC Molecular and Cell Biology, October 2012
DOI 10.1186/1471-2091-13-21
Pubmed ID
Authors

Xinwen Liang, Alaattin Kaya, Yan Zhang, Dung Tien Le, Deame Hua, Vadim N Gladyshev

Abstract

Methionine (Met) residues in proteins can be readily oxidized by reactive oxygen species to Met sulfoxide (MetO). MetO is a promising physiological marker of oxidative stress and its inefficient repair by MetO reductases (Msrs) has been linked to neurodegeneration and aging. Conventional methods of assaying MetO formation and reduction rely on chromatographic or mass spectrometry procedures, but the use of Met-rich proteins (MRPs) may offer a more streamlined alternative.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 2%
Canada 1 1%
Unknown 86 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 37%
Researcher 15 17%
Student > Bachelor 5 6%
Student > Master 5 6%
Professor 4 4%
Other 12 13%
Unknown 15 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 29%
Chemistry 17 19%
Biochemistry, Genetics and Molecular Biology 16 18%
Medicine and Dentistry 5 6%
Chemical Engineering 4 4%
Other 5 6%
Unknown 16 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2012.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#778
of 1,233 outputs
Outputs of similar age
#133,671
of 202,127 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#10
of 25 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,127 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.