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Ganjam virus/Nairobi sheep disease virus induces a pro-inflammatory response in infected sheep

Overview of attention for article published in Veterinary Research, October 2012
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Title
Ganjam virus/Nairobi sheep disease virus induces a pro-inflammatory response in infected sheep
Published in
Veterinary Research, October 2012
DOI 10.1186/1297-9716-43-71
Pubmed ID
Authors

Abid bin Tarif, Lidia Lasecka, Barbara Holzer, Michael D Baron

Abstract

Partly due to climate change, and partly due to changes of human habitat occupation, the impact of tick-borne viruses is increasing. Nairobi sheep disease virus (NSDV) and Ganjam virus (GV) are two names for the same virus, which causes disease in sheep and goats and is currently known to be circulating in India and East Africa. The virus is transmitted by ixodid ticks and causes a severe hemorrhagic disease. We have developed a real-time PCR assay for the virus genome and validated it in a pilot study of the pathogenicity induced by two different isolates of NSDV/GV. One isolate was highly adapted to tissue culture, grew in most cell lines tested, and was essentially apathogenic in sheep. The second isolate appeared to be poorly adapted to cell culture and retained pathogenicity in sheep. The real-time PCR assay for virus easily detected 4 copies or less of the viral genome, and allowed a quantitative measure of the virus in whole blood. Measurement of the changes in cytokine mRNAs showed similar changes to those observed in humans infected by the closely related virus Crimean Congo hemorrhagic fever virus.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 24%
Student > Ph. D. Student 6 13%
Student > Master 5 11%
Student > Doctoral Student 4 9%
Student > Bachelor 3 7%
Other 6 13%
Unknown 11 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 17%
Veterinary Science and Veterinary Medicine 6 13%
Medicine and Dentistry 6 13%
Biochemistry, Genetics and Molecular Biology 4 9%
Social Sciences 3 7%
Other 6 13%
Unknown 13 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2020.
All research outputs
#16,579,551
of 25,371,288 outputs
Outputs from Veterinary Research
#774
of 1,337 outputs
Outputs of similar age
#122,220
of 194,129 outputs
Outputs of similar age from Veterinary Research
#7
of 10 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,129 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.