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Mendeley readers
Attention Score in Context
| Title |
Ceramide and ceramide 1-phosphate in health and disease
|
|---|---|
| Published in |
Lipids in Health and Disease, February 2010
|
| DOI | 10.1186/1476-511x-9-15 |
| Pubmed ID | |
| Authors |
Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba, Antonio Gómez-Muñoz |
| Abstract |
Sphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides are the promotion of cell cycle arrest and the induction of apoptosis. Phosphorylation of ceramide produces ceramide 1-phosphate (C1P), which has opposite effects to ceramide. C1P is mitogenic and has prosurvival properties. In addition, C1P is an important mediator of inflammatory responses, an action that takes place through stimulation of cytosolic phospholipase A2, and the subsequent release of arachidonic acid and prostaglandin formation. All of the former actions are thought to be mediated by intracellularly generated C1P. However, the recent observation that C1P stimulates macrophage chemotaxis implicates specific plasma membrane receptors that are coupled to Gi proteins. Hence, it can be concluded that C1P has dual actions in cells, as it can act as an intracellular second messenger to promote cell survival, or as an extracellular receptor agonist to stimulate cell migration. |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Australia | 1 | <1% |
| Italy | 1 | <1% |
| Spain | 1 | <1% |
| Costa Rica | 1 | <1% |
| Unknown | 153 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 23% |
| Researcher | 33 | 20% |
| Student > Master | 16 | 10% |
| Student > Bachelor | 13 | 8% |
| Student > Doctoral Student | 9 | 6% |
| Other | 29 | 18% |
| Unknown | 24 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 54 | 34% |
| Biochemistry, Genetics and Molecular Biology | 27 | 17% |
| Medicine and Dentistry | 18 | 11% |
| Chemistry | 8 | 5% |
| Neuroscience | 3 | 2% |
| Other | 21 | 13% |
| Unknown | 30 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2015.
All research outputs
#4,080,229
of 22,684,168 outputs
Outputs from Lipids in Health and Disease
#270
of 1,438 outputs
Outputs of similar age
#23,997
of 165,021 outputs
Outputs of similar age from Lipids in Health and Disease
#5
of 25 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,438 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,021 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.