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Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes

Overview of attention for article published in Journal of Neuroinflammation, October 2012
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Title
Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes
Published in
Journal of Neuroinflammation, October 2012
DOI 10.1186/1742-2094-9-243
Pubmed ID
Authors

Nele Berghmans, Hubertine Heremans, Sandra Li, Erik Martens, Patrick Matthys, Lydia Sorokin, Jo Van Damme, Ghislain Opdenakker

Abstract

Neutrophil influx is an important sign of hyperacute neuroinflammation, whereas the entry of activated lymphocytes into the brain parenchyma is a hallmark of chronic inflammatory processes, as observed in multiple sclerosis (MS) and its animal models of experimental autoimmune encephalomyelitis (EAE). Clinically approved or experimental therapies for neuroinflammation act by blocking leukocyte penetration of the blood brain barrier. However, in view of unsatisfactory results and severe side effects, complementary therapies are needed. We have examined the effect of chlorite-oxidized oxyamylose (COAM), a potent antiviral polycarboxylic acid on EAE.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 19%
Student > Doctoral Student 5 14%
Student > Bachelor 5 14%
Researcher 5 14%
Student > Ph. D. Student 5 14%
Other 5 14%
Unknown 4 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 25%
Agricultural and Biological Sciences 8 22%
Neuroscience 5 14%
Immunology and Microbiology 4 11%
Medicine and Dentistry 2 6%
Other 4 11%
Unknown 4 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2012.
All research outputs
#17,489,487
of 25,654,806 outputs
Outputs from Journal of Neuroinflammation
#2,033
of 2,969 outputs
Outputs of similar age
#134,102
of 202,500 outputs
Outputs of similar age from Journal of Neuroinflammation
#15
of 23 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,969 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,500 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.