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Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates

Overview of attention for article published in BMC Immunology, October 2012
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3 X users

Citations

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41 Dimensions

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Title
Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates
Published in
BMC Immunology, October 2012
DOI 10.1186/1471-2172-13-57
Pubmed ID
Authors

Paul J Groot-Kormelink, Lindsay Fawcett, Paul D Wright, Martin Gosling, Toby C Kent

Abstract

Alveolar macrophages are one of the first lines of defence against invading pathogens and play a central role in modulating both the innate and acquired immune systems. By responding to endogenous stimuli within the lung, alveolar macrophages contribute towards the regulation of the local inflammatory microenvironment, the initiation of wound healing and the pathogenesis of viral and bacterial infections. Despite the availability of protocols for isolating primary alveolar macrophages from the lung these cells remain recalcitrant to expansion in-vitro and therefore surrogate cell types, such as monocyte derived macrophages and phorbol ester-differentiated cell lines (e.g. U937, THP-1, HL60) are frequently used to model macrophage function.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 29%
Student > Master 9 22%
Student > Ph. D. Student 9 22%
Professor 2 5%
Student > Bachelor 2 5%
Other 3 7%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 27%
Pharmacology, Toxicology and Pharmaceutical Science 7 17%
Biochemistry, Genetics and Molecular Biology 4 10%
Chemistry 3 7%
Immunology and Microbiology 3 7%
Other 8 20%
Unknown 5 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2012.
All research outputs
#17,670,096
of 22,684,168 outputs
Outputs from BMC Immunology
#375
of 588 outputs
Outputs of similar age
#134,445
of 183,259 outputs
Outputs of similar age from BMC Immunology
#7
of 10 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 588 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,259 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.