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Larval midgut modifications associated with Bti resistance in the yellow fever mosquito using proteomic and transcriptomic approaches

Overview of attention for article published in BMC Genomics, June 2012
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Title
Larval midgut modifications associated with Bti resistance in the yellow fever mosquito using proteomic and transcriptomic approaches
Published in
BMC Genomics, June 2012
DOI 10.1186/1471-2164-13-248
Pubmed ID
Authors

Guillaume Tetreau, Krishnareddy Bayyareddy, Christopher M Jones, Renaud Stalinski, Muhammad A Riaz, Margot Paris, Jean-Philippe David, Michael J Adang, Laurence Després

Abstract

Bacillus thuringiensis var. israelensis (Bti) is a natural larval mosquito pathogen producing pore-forming toxins targeting the midgut of Diptera larvae. It is used worldwide for mosquito control. Resistance mechanisms of an Aedes aegypti laboratory strain selected for 30 generations with field-collected leaf litter containing Bti toxins were investigated in larval midguts at two levels: 1. gene transcription using DNA microarray and RT-qPCR and 2. differential expression of brush border membrane proteins using DIGE (Differential In Gel Electrophoresis).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
France 1 <1%
United Kingdom 1 <1%
Tunisia 1 <1%
Slovenia 1 <1%
Unknown 112 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 21%
Student > Master 18 15%
Researcher 16 14%
Student > Doctoral Student 11 9%
Student > Bachelor 8 7%
Other 25 21%
Unknown 14 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 60 51%
Biochemistry, Genetics and Molecular Biology 15 13%
Environmental Science 6 5%
Immunology and Microbiology 5 4%
Unspecified 5 4%
Other 11 9%
Unknown 15 13%