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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Topoisomerase II alpha gene amplification is a favorable prognostic factor in patients with HER2-positive metastatic breast cancer treated with trastuzumab
|
|---|---|
| Published in |
Journal of Translational Medicine, October 2012
|
| DOI | 10.1186/1479-5876-10-212 |
| Pubmed ID | |
| Authors |
George Fountzilas, Christos Christodoulou, Mattheos Bobos, Vassiliki Kotoula, Anastasia G Eleftheraki, Ioannis Xanthakis, Anna Batistatou, George Pentheroudakis, Nikolaos Xiros, Irene Papaspirou, Anna Koumarianou, Pavlos Papakostas, Dimitrios Bafaloukos, Dimosthenis V Skarlos, Konstantine T Kalogeras |
| Abstract |
The vast majority of patients with HER2-positive metastatic breast cancer (MBC) treated with trastuzumab eventually develop resistance to this agent. There is an unmet need therefore, for identifying biological markers with possible prognostic/predictive value in such patients. The aim of this study was to investigate the prognostic role of topoisomerase II alpha gene (TOP2A) amplification and protein (TopoIIa) expression in patients treated with trastuzumab-containing regimens. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| Unknown | 48 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 20% |
| Student > Ph. D. Student | 7 | 14% |
| Other | 6 | 12% |
| Student > Master | 5 | 10% |
| Professor > Associate Professor | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 10 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 24% |
| Biochemistry, Genetics and Molecular Biology | 8 | 16% |
| Agricultural and Biological Sciences | 6 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Psychology | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 14 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2019.
All research outputs
#6,383,331
of 22,684,168 outputs
Outputs from Journal of Translational Medicine
#979
of 3,962 outputs
Outputs of similar age
#48,348
of 183,408 outputs
Outputs of similar age from Journal of Translational Medicine
#17
of 63 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 3,962 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,408 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.