Title |
Transbronchial biopsy is useful in predicting UIP pattern
|
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Published in |
Respiratory Research, October 2012
|
DOI | 10.1186/1465-9921-13-96 |
Pubmed ID | |
Authors |
Sara Tomassetti, Alberto Cavazza, Thomas V Colby, Jay H Ryu, Oriana Nanni, E Scarpi, Paola Tantalocco, Matteo Buccioli, Alessandra Dubini, Sara Piciucchi, Claudia Ravaglia, Christian Gurioli, Gian Luca Casoni, Carlo Gurioli, Micaela Romagnoli, Venerino Poletti |
Abstract |
Usual interstitial pneumonia (UIP), is a necessary feature pathologically or radiologically for the diagnosis of idiopathic pulmonary fibrosis (IPF). The predictive value of transbronchial biopsy (TBB) in identifying UIP is currently unknown. The objective of this study is to assess the accuracy with which histopathologic criteria of usual interstitial pneumonia (UIP) can be identified in transbronchial biopsy (TBB) and to assess the usefulness of TBBx in predicting a the diagnosis of UIP pattern. We conducted a retrospective blinded and controlled analysis of TBB specimens from 40 established cases of UIP and 24 non-UIP interstitial lung diseases. |
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