Title |
Variation in hemolytic activity of Brachyspira hyodysenteriae strains from pigs
|
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Published in |
Veterinary Research, June 2016
|
DOI | 10.1186/s13567-016-0353-x |
Pubmed ID | |
Authors |
Maxime Mahu, Nele De Pauw, Lien Vande Maele, Marc Verlinden, Filip Boyen, Richard Ducatelle, Freddy Haesebrouck, An Martel, Frank Pasmans |
Abstract |
Brachyspira hyodysenteriae is the primary cause of swine dysentery, which is responsible for major economic losses to the pig industry worldwide. The hemolytic activity of 10 B. hyodysenteriae strains isolated from stools of pigs with mild to mucohemorrhagic diarrhea was compared and seven hemolysis associated genes were sequenced. Hemolysis induced by these strains varied from strong to near absent. One weakly hemolytic B. hyodysenteriae strain showed sequence changes in five hemolysis associated genes (tlyA, tlyB, hemolysin III, hemolysin activation protein and hemolysin III channel protein) resulting in amino acid substitutions. The occurrence of weakly hemolytic strains identifiable as B. hyodysenteriae should be taken into account in swine dysentery diagnostics. The presence of these strains may affect herd dysentery status, with great impact on a farms trading opportunities. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Belgium | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 3% |
Unknown | 31 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 19% |
Student > Master | 5 | 16% |
Student > Ph. D. Student | 5 | 16% |
Student > Doctoral Student | 4 | 13% |
Other | 3 | 9% |
Other | 6 | 19% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 11 | 34% |
Agricultural and Biological Sciences | 6 | 19% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Immunology and Microbiology | 2 | 6% |
Unspecified | 1 | 3% |
Other | 1 | 3% |
Unknown | 6 | 19% |