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Receptor specificity and erythrocyte binding preferences of avian influenza viruses isolated from India

Overview of attention for article published in Virology Journal, October 2012
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Title
Receptor specificity and erythrocyte binding preferences of avian influenza viruses isolated from India
Published in
Virology Journal, October 2012
DOI 10.1186/1743-422x-9-251
Pubmed ID
Authors

Shailesh D Pawar, Saurabh S Parkhi, Santosh S Koratkar, Akhilesh C Mishra

Abstract

Hemagglutination (HA) and hemagglutination inhibition (HI) assays are conventionally used for detection and identification of influenza viruses. HI assay is also used for detection of antibodies against influenza viruses. Primarily turkey or chicken erythrocytes [red blood cells (RBCs)] are used in these assays, as they are large, nucleated, and sediment fast, which makes it easy to determine the titer. Human influenza viruses agglutinate RBCs from chicken, human, and guinea pig, but not from horse. Human influenza viruses bind preferentially to sialic acid (SA) linked to galactose (Gal) by α 2, 6 linkage (SA α 2, 6-Gal), whereas avian influenza (AI) viruses bind preferentially to SA α 2, 3-Gal linkages. With this background, the present study was undertaken to study erythrocyte binding preferences and receptor specificities of AI viruses isolated from India.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 25%
Researcher 11 25%
Student > Bachelor 5 11%
Student > Master 5 11%
Other 3 7%
Other 5 11%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 48%
Immunology and Microbiology 4 9%
Biochemistry, Genetics and Molecular Biology 3 7%
Chemistry 3 7%
Medicine and Dentistry 3 7%
Other 5 11%
Unknown 5 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2012.
All research outputs
#15,688,569
of 23,313,051 outputs
Outputs from Virology Journal
#1,980
of 3,095 outputs
Outputs of similar age
#117,564
of 185,209 outputs
Outputs of similar age from Virology Journal
#59
of 96 outputs
Altmetric has tracked 23,313,051 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,095 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.8. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 185,209 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.