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Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer

Overview of attention for article published in BMC Cancer, November 2012
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Title
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
Published in
BMC Cancer, November 2012
DOI 10.1186/1471-2407-12-505
Pubmed ID
Authors

Kristina Schee, Kjetil Boye, Torveig Weum Abrahamsen, Øystein Fodstad, Kjersti Flatmark

Abstract

MicroRNAs (miRNAs) regulate gene expression by binding to mRNA, and can function as oncogenes or tumor suppressors depending on the target. In this study, using qRT-PCR, we examined the expression of six miRNAs (miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145) in tumors from 193 prospectively recruited patients with colorectal cancer, and associations with clinicopathological parameters and patient outcome were analyzed. The miRNAs were chosen based on previous studies for their biomarker potential and suggested biological relevance in colorectal cancer.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Egypt 2 2%
Denmark 2 2%
United Kingdom 1 1%
Malaysia 1 1%
Unknown 92 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 28%
Researcher 22 22%
Student > Master 13 13%
Student > Bachelor 7 7%
Other 4 4%
Other 11 11%
Unknown 14 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 31%
Medicine and Dentistry 20 20%
Biochemistry, Genetics and Molecular Biology 17 17%
Veterinary Science and Veterinary Medicine 2 2%
Computer Science 2 2%
Other 9 9%
Unknown 18 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2012.
All research outputs
#18,319,742
of 22,684,168 outputs
Outputs from BMC Cancer
#5,416
of 8,249 outputs
Outputs of similar age
#140,571
of 184,200 outputs
Outputs of similar age from BMC Cancer
#75
of 111 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,249 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 184,200 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.