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Mendeley readers
Attention Score in Context
Title |
Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing
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Published in |
Molecular Neurodegeneration, June 2012
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DOI | 10.1186/1750-1326-7-30 |
Pubmed ID | |
Authors |
Yonghao Zhao, Yunshu Wang, Jiaye Yang, Xin Wang, Yingjun Zhao, Xian Zhang, Yun-wu Zhang |
Abstract |
β-site APP cleaving enzyme 1 (BACE1) cleaves β-amyloid precursor protein (APP) to initiate the production of β-amyloid (Aβ), the prime culprit in Alzheimer's disease (AD). Dysregulation of the intracellular trafficking of BACE1 may affect Aβ generation, contributing to AD pathology. In this study, we investigated whether BACE1 trafficking and BACE1-mediated APP processing/Aβ generation are affected by sorting nexin 12 (SNX12), a member of the sorting nexin (SNX) family that is involved in protein trafficking regulation. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Unknown | 62 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 22% |
Student > Ph. D. Student | 13 | 21% |
Student > Bachelor | 8 | 13% |
Student > Master | 7 | 11% |
Student > Doctoral Student | 5 | 8% |
Other | 7 | 11% |
Unknown | 9 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 27 | 43% |
Biochemistry, Genetics and Molecular Biology | 10 | 16% |
Neuroscience | 5 | 8% |
Psychology | 3 | 5% |
Engineering | 2 | 3% |
Other | 3 | 5% |
Unknown | 13 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2012.
All research outputs
#20,172,971
of 22,685,926 outputs
Outputs from Molecular Neurodegeneration
#830
of 844 outputs
Outputs of similar age
#148,422
of 164,540 outputs
Outputs of similar age from Molecular Neurodegeneration
#11
of 11 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 844 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,540 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.