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Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development

Overview of attention for article published in Virology Journal, November 2012
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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4 X users

Citations

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Readers on

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64 Mendeley
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Title
Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development
Published in
Virology Journal, November 2012
DOI 10.1186/1743-422x-9-263
Pubmed ID
Authors

Natalia Goñi, Andrés Iriarte, Victoria Comas, Martín Soñora, Pilar Moreno, Gonzalo Moratorio, Héctor Musto, Juan Cristina

Abstract

Influenza A virus (IAV) is a member of the family Orthomyxoviridae and contains eight segments of a single-stranded RNA genome with negative polarity. The first influenza pandemic of this century was declared in April of 2009, with the emergence of a novel H1N1 IAV strain (H1N1pdm) in Mexico and USA. Understanding the extent and causes of biases in codon usage is essential to the understanding of viral evolution. A comprehensive study to investigate the effect of selection pressure imposed by the human host on the codon usage of an emerging, pandemic IAV strain and the trends in viral codon usage involved over the pandemic time period is much needed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Argentina 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 25%
Researcher 12 19%
Student > Bachelor 9 14%
Student > Master 5 8%
Professor > Associate Professor 3 5%
Other 9 14%
Unknown 10 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 31%
Biochemistry, Genetics and Molecular Biology 10 16%
Medicine and Dentistry 7 11%
Immunology and Microbiology 5 8%
Veterinary Science and Veterinary Medicine 3 5%
Other 4 6%
Unknown 15 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2012.
All research outputs
#13,371,661
of 22,685,926 outputs
Outputs from Virology Journal
#1,350
of 3,030 outputs
Outputs of similar age
#99,674
of 183,504 outputs
Outputs of similar age from Virology Journal
#34
of 90 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,030 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,504 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.