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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Ganglioside GD2-specific trifunctional surrogate antibody Surek demonstrates therapeutic activity in a mouse melanoma model
|
|---|---|
| Published in |
Journal of Translational Medicine, November 2012
|
| DOI | 10.1186/1479-5876-10-219 |
| Pubmed ID | |
| Authors |
Peter Ruf, Beatrix Schäfer, Nina Eissler, Ralph Mocikat, Juergen Hess, Matthias Plöscher, Susanne Wosch, Ivonne Suckstorff, Christine Zehetmeier, Horst Lindhofer |
| Abstract |
Trifunctional bispecific antibodies (trAb) are a special class of bispecific molecules recruiting and activating T cells and accessory immune cells simultaneously at the targeted tumor. The new trAb Ektomab that targets the melanoma-associated ganglioside antigen GD2 and the signaling molecule human CD3 (hCD3) on T cells demonstrated potent T-cell activation and tumor cell destruction in vitro. However, the relatively low affinity for the GD2 antigen raised the question of its therapeutic capability. To further evaluate its efficacy in vivo it was necessary to establish a mouse model. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Peru | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 33 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 21% |
| Student > Ph. D. Student | 6 | 18% |
| Other | 4 | 12% |
| Researcher | 3 | 9% |
| Professor | 2 | 6% |
| Other | 5 | 15% |
| Unknown | 6 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 11 | 33% |
| Biochemistry, Genetics and Molecular Biology | 5 | 15% |
| Immunology and Microbiology | 5 | 15% |
| Medicine and Dentistry | 5 | 15% |
| Engineering | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 6 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2021.
All research outputs
#4,488,844
of 22,685,926 outputs
Outputs from Journal of Translational Medicine
#713
of 3,962 outputs
Outputs of similar age
#34,080
of 183,514 outputs
Outputs of similar age from Journal of Translational Medicine
#13
of 58 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,962 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,514 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.