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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Right heart function deteriorates in breast cancer patients undergoing anthracycline-based chemotherapy
|
|---|---|
| Published in |
Echo Research & Practice, September 2016
|
| DOI | 10.1530/erp-16-0020 |
| Pubmed ID | |
| Authors |
Kevin Emery Boczar, Olexiy Aseyev, Jeffrey Sulpher, Christopher Johnson, Ian G. Burwash, Michele Turek, Susan Dent, Girish Dwivedi |
| Abstract |
Cardiotoxicity from anthracycline-based chemotherapy is an important cause of early and late morbidity and mortality in breast cancer patients. Left ventricular (LV) function is assessed for patients receiving anthracycline based chemotherapy to identify cardiotoxicity. Animal studies however, suggest that right ventricular (RV) function may be a more sensitive measure to detect LV dysfunction. The purpose of this pilot study was to determine if breast cancer patients undergoing anthracycline-based chemotherapy experience RV dysfunction. Forty-nine breast cancer patients undergoing anthracycline-based chemotherapy at The Ottawa Hospital between November 2007 and March 2013 and who had 2 echocardiograms performed at least 3 months apart were retrospectively identified. Right atrial area (RAA), right ventricular fractional area change (RV FAC) and RV longitudinal-strain of the free wall (RV LSFW) were evaluated according to the American Society of Echocardiography guidelines. The majority (48/49) of patients were females with an average age of 53.4. From baseline to follow-up study, average LV ejection fraction (LVEF) decreased from 62.22 to 57.4% (p=0.04). During the same time period, the mean RAA increased from 12.1 cm2 to 13.8 cm2 (P = 0.02), mean RV FAC decreased (P = 0.01) from 48.3% to 42.1% and mean RV LSFW worsened from -16.2% to -13.81% (P = 0.04). This study demonstrates that breast cancer patients receiving anthracycline-based chemotherapy experience adverse effects on both right atrial size and RV function. Further studies are required to determine the impact of these adverse effects on right heart function and whether this represents an earlier marker of cardiotoxicity. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 27% |
| Venezuela, Bolivarian Republic of | 1 | 5% |
| Ecuador | 1 | 5% |
| Dominican Republic | 1 | 5% |
| Australia | 1 | 5% |
| Mexico | 1 | 5% |
| India | 1 | 5% |
| Paraguay | 1 | 5% |
| Unknown | 9 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 77% |
| Practitioners (doctors, other healthcare professionals) | 3 | 14% |
| Science communicators (journalists, bloggers, editors) | 2 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 15% |
| Student > Master | 6 | 11% |
| Student > Ph. D. Student | 5 | 9% |
| Student > Bachelor | 5 | 9% |
| Professor > Associate Professor | 4 | 7% |
| Other | 10 | 18% |
| Unknown | 17 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 44% |
| Psychology | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Unspecified | 1 | 2% |
| Mathematics | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 23 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2017.
All research outputs
#2,366,318
of 25,377,790 outputs
Outputs from Echo Research & Practice
#59
of 268 outputs
Outputs of similar age
#40,064
of 348,375 outputs
Outputs of similar age from Echo Research & Practice
#2
of 7 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 268 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,375 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.