@jmuiuc @NCITomMisteli @faucla @zocean636 @LoreBonimba @muyu_wendy_yang sorry! and thank you for fixing it. For TAD finding we have also done some dim-red methods like https://t.co/sRtncGFZD6… but its hard to include everything in this already very rich re
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Sometimes people choose to model complex data (like Hi-C) with complex models. I really like this method because it uses basic regularization to induce a more complicated pattern in the predictions. Happy to see both the paper and the episode out! https://
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From Sushmita Roy: GRiNCH: simultaneous smoothing and detection of topological units of genome organization from sparse chromatin contact count matrices with matrix factorization https://t.co/jnRu6Q0fzB
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RT @BioDecoded: GRiNCH: simultaneous smoothing and detection of topological units of genome organization from sparse chromatin contact coun…