Title |
Optimal vaccination schedule search using genetic algorithm over MPI technology
|
---|---|
Published in |
BMC Medical Informatics and Decision Making, November 2012
|
DOI | 10.1186/1472-6947-12-129 |
Pubmed ID | |
Authors |
Cristiano Calonaci, Ferdinando Chiacchio, Francesco Pappalardo |
Abstract |
Immunological strategies that achieve the prevention of tumor growth are based on the presumption that the immune system, if triggered before tumor onset, could be able to defend from specific cancers. In supporting this assertion, in the last decade active immunization approaches prevented some virus-related cancers in humans. An immunopreventive cell vaccine for the non-virus-related human breast cancer has been recently developed. This vaccine, called Triplex, targets the HER-2-neu oncogene in HER-2/neu transgenic mice and has shown to almost completely prevent HER-2/neu-driven mammary carcinogenesis when administered with an intensive and life-long schedule. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
India | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 2 | 13% |
Student > Master | 2 | 13% |
Student > Ph. D. Student | 2 | 13% |
Student > Bachelor | 1 | 7% |
Professor | 1 | 7% |
Other | 2 | 13% |
Unknown | 5 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Computer Science | 3 | 20% |
Engineering | 2 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Economics, Econometrics and Finance | 1 | 7% |
Nursing and Health Professions | 1 | 7% |
Other | 2 | 13% |
Unknown | 5 | 33% |