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Self-reported vs. objectively assessed adherence to inhaled corticosteroids in asthma

Overview of attention for article published in Asthma Research and Practice, May 2021
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  • Above-average Attention Score compared to outputs of the same age (58th percentile)

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Title
Self-reported vs. objectively assessed adherence to inhaled corticosteroids in asthma
Published in
Asthma Research and Practice, May 2021
DOI 10.1186/s40733-021-00072-2
Pubmed ID
Authors

Frodi Fridason Jensen, Kjell E. J. Håkansson, Britt Overgaard Nielsen, Ulla Møller Weinreich, Charlotte Suppli Ulrik

Abstract

Adherence to inhaled corticosteroids (ICS) in asthma is vital for disease control. However, obtaining reliable and clinically useful measures of adherence remains a major challenge. We investigated the association between patient-reported adherence and objectively measured adherence based on filled prescriptions with inhaled corticosteroids in adults with asthma. In total, 178 patients with asthma were asked to self-assess adherence during routine visits at a respiratory outpatient clinic. Self-assessment was performed using Foster score ("How many days in a 7-day week do you take your medication as prescribed?", with the answer divided by 7). Objective adherence was calculated as medication possession ratio (MPR). Bivariate and multivariable linear regression, adjusted for age, sex, FEV1, GINA treatment step, excessive use of SABA, and history of exacerbations were used for analyses. Of the included patients, 87.6% reported a Foster score of 100%, while the mean ICS MPR was 54.0% (SD 25%). Complex regimens such as twice-daily dosing or dual inhaler-use were associated with lower adherence (p = 0.015 and p < 0.001, respectively). Foster score was predictive of ICS MPR, with an absolute 32% increase in MPR between patients reporting Foster scores of 0 and 100% (95% CI 13-50%, p < 0.001). Female sex predicted higher ICS MPR (p = 0.019). Previous asthma-related hospitalization(s) predicted lower ICS MPR (p = 0.039). Although a weak association was found between Foster score and ICS MPR, findings do not support the use of Foster score, and by that self-reported adherence, as a reliable marker of controller adherence in asthma due to significant mismatch between patient-reported adherence and MPR. Future studies should address the complex interplay between patient-reported and objectively assessed adherence to controller medication in asthma.

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The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 15%
Student > Ph. D. Student 3 15%
Student > Master 2 10%
Lecturer 1 5%
Librarian 1 5%
Other 3 15%
Unknown 7 35%
Readers by discipline Count As %
Medicine and Dentistry 10 50%
Business, Management and Accounting 2 10%
Biochemistry, Genetics and Molecular Biology 1 5%
Unknown 7 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2021.
All research outputs
#13,028,980
of 23,308,124 outputs
Outputs from Asthma Research and Practice
#42
of 83 outputs
Outputs of similar age
#182,083
of 447,666 outputs
Outputs of similar age from Asthma Research and Practice
#3
of 4 outputs
Altmetric has tracked 23,308,124 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 83 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,666 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.