Title |
Antibiotic resistance pattern and frequency of cagA and vacA genes in Helicobacter pylori strains isolated from patients in Tabriz city, Iran
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Published in |
BMC Research Notes, May 2021
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DOI | 10.1186/s13104-021-05633-5 |
Pubmed ID | |
Authors |
Farnaz Rasi-Bonab, Abolfazl Jafari-Sales, Mohammad Amin Shaverdi, Tahereh Navidifar, Morteza Saki, Atosa Ghorbani, Abimbola Olumide Adekanmbi, Behboud Jafari, Sara Naebi |
Abstract |
Helicobacter pylori is one of the most common causes of gastric infections in humans. It is estimated that approximately 50% of people around the world are infected with this bacterium. This study aimed to determine the antibiotic resistance pattern, as well as the frequency of cagA and vacA genes in H. pylori isolates obtained from patients in the clinical centers in Tabriz city, Iran. The culture method detected 100 (45.25%) H. pylori isolates from 221 biopsy samples during 3 years. The results showed that 63% and 81% of the isolates were positive for cagA and vacA genes, respectively. The highest resistance of isolates was seen against metronidazole (79%) and amoxicillin (36%), respectively. Also, the isolates showed the least resistance to tetracycline (8%). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 2 | 17% |
Student > Master | 2 | 17% |
Student > Bachelor | 1 | 8% |
Lecturer | 1 | 8% |
Professor > Associate Professor | 1 | 8% |
Other | 0 | 0% |
Unknown | 5 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 2 | 17% |
Environmental Science | 1 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
Nursing and Health Professions | 1 | 8% |
Immunology and Microbiology | 1 | 8% |
Other | 1 | 8% |
Unknown | 5 | 42% |