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ERβ1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR

Overview of attention for article published in Breast Cancer Research, November 2012
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Title
ERβ1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR
Published in
Breast Cancer Research, November 2012
DOI 10.1186/bcr3358
Pubmed ID
Authors

Christoforos Thomas, Gayani Rajapaksa, Fotis Nikolos, Ruixin Hao, Anne Katchy, Catherine W McCollum, Maria Bondesson, Phil Quinlan, Alastair Thompson, Savitri Krishnamurthy, Francisco J Esteva, Jan-Åke Gustafsson

Abstract

Epithelial to mesenchymal transition (EMT) is associated with the basal-like breast cancer phenotypes. 60% of basal-like cancers have been shown to express wild-type estrogen receptor beta (ERbeta1). However, it is still unclear whether the ERbeta expression is related to EMT, invasion and metastasis in breast cancer. In the present study, we examined whether ERbeta1 through regulating EMT can influence invasion and metastasis in basal-like cancers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 1%
Unknown 74 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 24%
Student > Ph. D. Student 16 21%
Student > Master 10 13%
Student > Bachelor 6 8%
Student > Postgraduate 3 4%
Other 8 11%
Unknown 14 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 31%
Biochemistry, Genetics and Molecular Biology 20 27%
Medicine and Dentistry 8 11%
Engineering 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 5 7%
Unknown 16 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2012.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,882
of 2,052 outputs
Outputs of similar age
#159,937
of 179,074 outputs
Outputs of similar age from Breast Cancer Research
#29
of 33 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,074 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.