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A standard numbering scheme for thiamine diphosphate-dependent decarboxylases

Overview of attention for article published in BMC Molecular and Cell Biology, November 2012
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Title
A standard numbering scheme for thiamine diphosphate-dependent decarboxylases
Published in
BMC Molecular and Cell Biology, November 2012
DOI 10.1186/1471-2091-13-24
Pubmed ID
Authors

Constantin Vogel, Michael Widmann, Martina Pohl, Jürgen Pleiss

Abstract

Standard numbering schemes for families of homologous proteins allow for the unambiguous identification of functionally and structurally relevant residues, to communicate results on mutations, and to systematically analyse sequence-function relationships in protein families. Standard numbering schemes have been successfully implemented for several protein families, including lactamases and antibodies, whereas a numbering scheme for the structural family of thiamine-diphosphate (ThDP) -dependent decarboxylases, a large subfamily of the class of ThDP-dependent enzymes encompassing pyruvate-, benzoylformate-, 2-oxo acid-, indolpyruvate- and phenylpyruvate decarboxylases, benzaldehyde lyase, acetohydroxyacid synthases and 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase (MenD) is still missing.Despite a high structural similarity between the members of the ThDP-dependent decarboxylases, their sequences are diverse and make a pairwise sequence comparison of protein family members difficult.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 4%
United Kingdom 1 2%
Unknown 54 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 28%
Student > Master 6 11%
Student > Bachelor 6 11%
Professor 5 9%
Student > Doctoral Student 3 5%
Other 12 21%
Unknown 9 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 49%
Biochemistry, Genetics and Molecular Biology 5 9%
Chemistry 4 7%
Engineering 3 5%
Computer Science 2 4%
Other 4 7%
Unknown 11 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2012.
All research outputs
#17,285,036
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#778
of 1,233 outputs
Outputs of similar age
#190,440
of 284,350 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#11
of 25 outputs
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So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.