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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies
|
|---|---|
| Published in |
BMC Cancer, November 2011
|
| DOI | 10.1186/1471-2407-11-500 |
| Pubmed ID | |
| Authors |
Angela Hui, Christine How, Emma Ito, Fei-Fei Liu |
| Abstract |
Micro-RNAs (miRs) are important regulators of mRNA and protein expression; the ability of miR expression profilings to distinguish different cancer types and classify their sub-types has been well-described. They also represent a novel biological entity with potential value as tumour biomarkers, which can improve diagnosis, prognosis, and monitoring of treatment response for human cancers. This endeavour has been greatly facilitated by the stability of miRs in formalin-fixed paraffin-embedded (FFPE) tissues, and their detection in circulation. This review will summarize some of the key dysregulated miRs described to date in human epithelial malignancies, and their potential value as molecular bio-markers in FFPE tissues and blood samples. There remain many challenges in this domain, however, with the evolution of different platforms, the complexities of normalizing miR profiling data, and the importance of evaluating sufficiently-powered training and validation cohorts. Nonetheless, well-conducted miR profiling studies should contribute important insights into the molecular aberrations driving human cancer development and progression. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Romania | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 41% |
| Student > Ph. D. Student | 16 | 26% |
| Student > Postgraduate | 3 | 5% |
| Student > Bachelor | 2 | 3% |
| Lecturer | 2 | 3% |
| Other | 7 | 11% |
| Unknown | 6 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 31% |
| Medicine and Dentistry | 14 | 23% |
| Biochemistry, Genetics and Molecular Biology | 13 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Nursing and Health Professions | 1 | 2% |
| Other | 2 | 3% |
| Unknown | 10 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2012.
All research outputs
#20,688,303
of 25,411,814 outputs
Outputs from BMC Cancer
#5,987
of 8,983 outputs
Outputs of similar age
#203,720
of 246,045 outputs
Outputs of similar age from BMC Cancer
#62
of 84 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,983 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.