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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The inflammatory protein Pentraxin 3 in cardiovascular disease
|
|---|---|
| Published in |
Immunity & Ageing, August 2016
|
| DOI | 10.1186/s12979-016-0080-1 |
| Pubmed ID | |
| Authors |
Francesco Fornai, Albino Carrizzo, Maurizio Forte, Mariateresa Ambrosio, Antonio Damato, Michela Ferrucci, Francesca Biagioni, Carla Busceti, Annibale A. Puca, Carmine Vecchione |
| Abstract |
The acute phase protein Pentraxin 3 (PTX3) plays a non-redundant role as a soluble pattern recognition receptor for selected pathogens and it represents a rapid biomarker for primary local activation of innate immunity and inflammation. Recent evidence indicates that PTX3 exerts an important role in modulating the cardiovascular system in humans and experimental models. In particular, there are conflicting points concerning the effects of PTX3 in cardiovascular diseases (CVD) since several observations indicate a cardiovascular protective effect of PTX3 while others speculate that the increased plasma levels of PTX3 in subjects with CVD correlate with disease severity and with poor prognosis in elderly patients. In the present review, we discuss the multifaceted effects of PTX3 on the cardiovascular system focusing on its involvement in atherosclerosis, endothelial function, hypertension, myocardial infarction and angiogenesis. This may help to explain how the specific modulation of PTX3 such as the use of different dosing, time, and target organs could help to contain different vascular diseases. These opposite actions of PTX3 will be emphasized concerning the modulation of cardiovascular system where potential therapeutic implications of PTX3 in humans are discussed. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| United Kingdom | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 97 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 21% |
| Student > Master | 13 | 13% |
| Student > Bachelor | 10 | 10% |
| Researcher | 9 | 9% |
| Student > Doctoral Student | 5 | 5% |
| Other | 20 | 21% |
| Unknown | 20 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 29% |
| Biochemistry, Genetics and Molecular Biology | 13 | 13% |
| Agricultural and Biological Sciences | 7 | 7% |
| Neuroscience | 4 | 4% |
| Veterinary Science and Veterinary Medicine | 3 | 3% |
| Other | 15 | 15% |
| Unknown | 27 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2016.
All research outputs
#14,858,374
of 22,883,326 outputs
Outputs from Immunity & Ageing
#220
of 374 outputs
Outputs of similar age
#207,813
of 341,487 outputs
Outputs of similar age from Immunity & Ageing
#3
of 3 outputs
Altmetric has tracked 22,883,326 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 374 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,487 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.