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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PTENgenomic deletion predicts prostate cancer recurrence and is associated with low AR expression and transcriptional activity
|
|---|---|
| Published in |
BMC Cancer, November 2012
|
| DOI | 10.1186/1471-2407-12-543 |
| Pubmed ID | |
| Authors |
Khalil Choucair, Joshua Ejdelman, Fadi Brimo, Armen Aprikian, Simone Chevalier, Jacques Lapointe |
| Abstract |
Prostate cancer (PCa), a leading cause of cancer death in North American men, displays a broad range of clinical outcome from relatively indolent to lethal metastatic disease. Several genomic alterations have been identified in PCa which may serve as predictors of progression. PTEN, (10q23.3), is a negative regulator of the phosphatidylinositol 3-kinase (PIK3)/AKT survival pathway and a tumor suppressor frequently deleted in PCa. The androgen receptor (AR) signalling pathway is known to play an important role in PCa and its blockade constitutes a commonly used treatment modality. In this study, we assessed the deletion status of PTEN along with AR expression levels in 43 primary PCa specimens with clinical follow-up. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Canada | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 54 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 26% |
| Researcher | 10 | 18% |
| Student > Bachelor | 9 | 16% |
| Professor | 3 | 5% |
| Student > Postgraduate | 3 | 5% |
| Other | 11 | 19% |
| Unknown | 6 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 32% |
| Medicine and Dentistry | 14 | 25% |
| Biochemistry, Genetics and Molecular Biology | 9 | 16% |
| Nursing and Health Professions | 1 | 2% |
| Unspecified | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 12 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2012.
All research outputs
#18,321,703
of 22,687,320 outputs
Outputs from BMC Cancer
#5,415
of 8,249 outputs
Outputs of similar age
#214,138
of 275,925 outputs
Outputs of similar age from BMC Cancer
#69
of 106 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,249 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,925 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.