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Prevalence of hepatitis B and clinical outcomes in inflammatory bowel disease patients in a viral-endemic region

Overview of attention for article published in BMC Gastroenterology, August 2016
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Title
Prevalence of hepatitis B and clinical outcomes in inflammatory bowel disease patients in a viral-endemic region
Published in
BMC Gastroenterology, August 2016
DOI 10.1186/s12876-016-0516-2
Pubmed ID
Authors

Heyson C. H. Chan, Vincent W. S. Wong, Grace L. H. Wong, Whitney Tang, Justin C. Y. Wu, Siew C. Ng

Abstract

Little is known of the prevalence of hepatitis B virus (HBV) infection and its effect on choice of therapy and disease course in patients with inflammatory bowel disease (IBD). We assessed the prevalence of HBV in Hong Kong as well as determinants of altered transaminases, effects of HBV infection on therapeutic strategy and clinical course in IBD. In this retrospective cohort, hepatitis B surface antigen (HBsAg), liver function tests, and IBD disease characteristics were recorded. Logistic regression was used to identify factors associated with altered transaminases. Four hundred six IBD patients were recruited. HBV infection was found in 5.7 % patients in Hong Kong. The use of steroids (OR, 2.52; p = 0.010) and a previous history of surgery (OR 2.33; p = 0.026) were associated with altered transaminases in IBD. There was no significant difference in disease control and use of IBD medication between HBsAg-positive and HBsAg-negative IBD patients. The prevalence of HBV among patients with IBD in Hong Kong (5.7 %) is similar to that of general population (~7 %). There was no difference in disease control and use of IBD medication between subjects with or without HBV.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Professor 3 12%
Other 2 8%
Student > Ph. D. Student 2 8%
Student > Bachelor 2 8%
Other 2 8%
Unknown 10 38%
Readers by discipline Count As %
Medicine and Dentistry 10 38%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Nursing and Health Professions 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 11 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2016.
All research outputs
#20,338,537
of 22,884,315 outputs
Outputs from BMC Gastroenterology
#1,366
of 1,752 outputs
Outputs of similar age
#300,229
of 343,744 outputs
Outputs of similar age from BMC Gastroenterology
#19
of 30 outputs
Altmetric has tracked 22,884,315 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,752 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.