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Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood–brain barrier through paracellular transmigration and ERK activation

Overview of attention for article published in Journal of Neuroinflammation, October 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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2 patents
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1 research highlight platform

Citations

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78 Dimensions

Readers on

mendeley
76 Mendeley
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1 CiteULike
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Title
Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood–brain barrier through paracellular transmigration and ERK activation
Published in
Journal of Neuroinflammation, October 2012
DOI 10.1186/1742-2094-9-245
Pubmed ID
Authors

Divya Sagar, Anne Lamontagne, Catherine A Foss, Zafar K Khan, Martin G Pomper, Pooja Jain

Abstract

Transmigration of circulating dendritic cells (DCs) into the central nervous system (CNS) across the blood-brain barrier (BBB) has not thus far been investigated. An increase in immune cell infiltration across the BBB, uncontrolled activation and antigen presentation are influenced by chemokines. Chemokine ligand 2 (CCL2) is a potent chemoattractant known to be secreted by the BBB but has not been implicated in the recruitment of DCs specifically at the BBB.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Germany 1 1%
Unknown 74 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 34%
Researcher 18 24%
Student > Bachelor 7 9%
Student > Master 7 9%
Other 4 5%
Other 8 11%
Unknown 6 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 30%
Medicine and Dentistry 12 16%
Immunology and Microbiology 11 14%
Neuroscience 9 12%
Biochemistry, Genetics and Molecular Biology 8 11%
Other 4 5%
Unknown 9 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2022.
All research outputs
#4,338,924
of 23,506,079 outputs
Outputs from Journal of Neuroinflammation
#824
of 2,718 outputs
Outputs of similar age
#31,834
of 184,947 outputs
Outputs of similar age from Journal of Neuroinflammation
#3
of 22 outputs
Altmetric has tracked 23,506,079 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,718 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 184,947 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.