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Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

Overview of attention for article published in Virology Journal, November 2012
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Title
Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein
Published in
Virology Journal, November 2012
DOI 10.1186/1743-422x-9-286
Pubmed ID
Authors

Jian Luo, Dan Zheng, Wenjie Zhang, Fang Fang, Hanzhong Wang, Ying Sun, Yahong Ding, Chengfei Xu, Quanjiao Chen, Hongbo Zhang, Ding Huang, Bing Sun, Ze Chen

Abstract

The highly conserved nucleoprotein (NP) is an internal protein of influenza virus and is capable of inducing cross-protective immunity against different influenza A viruses, making it a main target of universal influenza vaccine. In current study, we characterized the immune response induced by DNA prime-intranasal protein boost strategy based on NP (A/PR/8/34, H1N1) in mouse model, and evaluated its protection ability against a lethal dose challenge of influenza virus.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 39%
Student > Master 6 26%
Professor > Associate Professor 2 9%
Researcher 2 9%
Professor 1 4%
Other 2 9%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 35%
Medicine and Dentistry 4 17%
Biochemistry, Genetics and Molecular Biology 3 13%
Immunology and Microbiology 2 9%
Business, Management and Accounting 1 4%
Other 3 13%
Unknown 2 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2012.
All research outputs
#18,321,703
of 22,687,320 outputs
Outputs from Virology Journal
#2,424
of 3,030 outputs
Outputs of similar age
#214,506
of 276,424 outputs
Outputs of similar age from Virology Journal
#79
of 94 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,030 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,424 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.